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Topics:  image analysis, personalized medicine, tissue phenomics, data mining

Five Major Benefits of Tissue Phenomics®

Aug 8, 2016 3:00:00 AM

Seeing is believing – this is an important aspect of Tissue Phenomics, where cellular structures in tissue slides taken from patients are investigated in real space. Observing directly what type of structures form and what kind of interactions take place is in general of much higher value than concluding indirectly from other type of data. I experienced this factor very clearly thirty years ago when people speculated about the atomic structure on the surfaces of matter from indirect measurement. When we could, however, image atomic structures directly, it became obvious that most of those speculations were wrong. This is the reason why even for a genetic disease like cancer, genetic information could not push histology aside. Observing the structures and the interactions in tissue slides on the cell level enables insights into the disease of a specific person that is decisive and cannot be created otherwise. Tissue Phenomics builds upon histological information and pathologists’ knowledge and is by no means about replacing it. The mission is rather to gain an even deeper insight into biological processes detectable in cell structures for the enablement of new and successful treatments of patients and their specific diseases. In the beginning there was the question how far one can get with the Tissue Phenomics approach, or more concretely, how far can we go beyond what the experts already know today? What can be achieved when the computer investigates all kind of cell patterns in tissue and correlate them with biological and medical relevance and meaning, represented e.g. by clinical outcome? Today we know better.

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